@font-face{font-family:Research;src:url(/medical-research-2026-10-01-v1/fonts/Inter-Regular.ttf)format("truetype");font-weight:400;font-display:swap}@font-face{font-family:Research;src:url(/medical-research-2026-10-01-v1/fonts/Inter-Medium.ttf)format("truetype");font-weight:500;font-display:swap}@font-face{font-family:Research;src:url(/medical-research-2026-10-01-v1/fonts/Inter-SemiBold.ttf)format("truetype");font-weight:600;font-display:swap}@font-face{font-family:Research;src:url(/medical-research-2026-10-01-v1/fonts/Inter-Bold.ttf)format("truetype");font-weight:700;font-display:swap}:root{--paper:#f3f4f0;--ink:#08151e;--muted:#4b5d68;--line:#b9cbd2;--accent:#12628b;--wash:#d9edf5;--stage:#031015;--page-gutter:clamp(24px,4.7vw,80px);color:var(--ink);background:var(--paper);font-synthesis:none;scroll-behavior:auto;color-scheme:light;scroll-padding-top:24px;font-family:Research,sans-serif}*{box-sizing:border-box}body{margin:0;font-size:17px;line-height:1.6}h1,h2,h3,p,figure{margin:0}h1,h2,h3{text-wrap:balance;line-height:1.13}h1{letter-spacing:-.04em;font-size:clamp(56px,6.25vw,96px);font-weight:400}h2{letter-spacing:-.035em;font-size:clamp(30px,3.4vw,52px);font-weight:500}h3{letter-spacing:-.02em;font-size:24px;font-weight:500}a{color:inherit;text-underline-offset:5px;text-decoration-thickness:1px}button,input,select,textarea{font:inherit;color:inherit}button,a,input,select,textarea,summary{-webkit-tap-highlight-color:transparent}button,summary{cursor:pointer}button{border:1px solid var(--line);background:0 0}button:disabled{opacity:.6;cursor:wait}button:hover,a:hover{filter:brightness(.85)}a:focus-visible,button:focus-visible,summary:focus-visible,input:focus-visible,select:focus-visible,textarea:focus-visible{outline-offset:5px;outline:3px solid #2389b5}::selection{color:#031015;background:#a0dcf1}input,textarea{caret-color:var(--accent)}*{scrollbar-color:#8ba5af var(--paper);scrollbar-width:thin}[hidden]{display:none!important}.sr-only{clip:rect(0,0,0,0);white-space:nowrap;border:0;width:1px;height:1px;margin:-1px;padding:0;position:absolute;overflow:hidden}.skip{z-index:100;background:var(--paper);padding:12px;position:fixed;top:12px;left:12px;transform:translateY(-150%)}.skip:focus{transform:none}.wrap{width:100%;padding-inline:var(--page-gutter);max-width:1760px;margin:auto}.section{border-top:1px solid var(--line);padding-block:88px;scroll-margin-top:24px}.section-head{justify-content:space-between;align-items:baseline;gap:30px;margin-bottom:32px;display:flex}.section-intro{max-width:72ch;color:var(--muted);margin-top:18px}.button{border:1px solid var(--accent);border-radius:4px;justify-content:center;align-items:center;min-height:50px;padding:12px 28px;font-weight:500;text-decoration:none;display:inline-flex}.primary{color:#fff;background:#4c9ec5;border-color:#4c9ec5}.text-link{border-bottom:1px solid #6baccc;padding-bottom:4px;text-decoration:none;display:inline-block}.hero-actions{align-items:center;gap:32px;display:flex}.opening{background:#f0f1ec;position:relative;overflow:hidden}.opening-dark{background:var(--stage);color:#f5f8f9}.header{height:70px;padding-inline:var(--page-gutter);z-index:3;border-bottom:1px solid #a7beca66;justify-content:space-between;align-items:center;display:flex;position:relative}.brand{letter-spacing:.2em;font-size:25px;font-weight:500;line-height:1;text-decoration:none}.header nav{gap:36px;font-size:14px;display:flex}.header nav a{text-decoration:none}.menu-button{display:none}.hero{height:556px;padding-inline:var(--page-gutter);position:relative}.hero-copy{z-index:2;max-width:575px;padding-top:78px;position:relative}.hero-subtitle{letter-spacing:-.02em;margin-top:26px;font-size:26px;line-height:1.3}.hero-intro{color:var(--muted);white-space:nowrap;margin-top:26px;font-size:19px;line-height:1.4}.hero-actions{margin-top:27px;font-size:17px}.hero-image{width:60%;height:545px;position:absolute;top:70px;right:0}.hero-image img{object-fit:cover;width:100%;height:100%;display:block}.concept-caption{right:var(--page-gutter);color:var(--muted);z-index:2;font-size:10px;position:absolute;bottom:18px}.scene-switch{z-index:2;gap:14px;display:flex;position:absolute;bottom:28px;left:54%}.scene-switch button{color:#e2f5fc;background:#03101599;border-color:#afc6ce;min-width:125px;padding:14px 24px}.scene-switch button[aria-pressed=true]{background:#154454b3;border-color:#87d6f0}.opening-dark .hero-intro,.opening-dark .concept-caption{color:#bbccd3}.opening-dark .primary{color:#031015;background:#8edcf2;border-color:#8edcf2}.opening-dark .hero-subtitle{color:#ecf5f7}.opening-dark .hero-image{width:66%;height:545px;top:65px}.opening-dark .hero{height:550px}.opening-dark .header{height:65px}.opening-dark .hero-copy{padding-top:79px}.opening-dark .concept-caption{bottom:96px}.opening-dark .hero-image:after{content:"";background:linear-gradient(90deg,var(--stage),transparent 10%);pointer-events:none;position:absolute;inset:0}.hero-image img{transition:filter .6s ease-out}.opening[data-scene=sound] .hero-image img{filter:saturate(.3)brightness(.7)}.opening[data-scene=light] .hero-image img{filter:saturate(.7)brightness(1.12)}body[data-variant=astra-immersive] .header{height:87px;margin-inline:3.5%;padding-inline:1.5%;font-size:18px}body[data-variant=astra-immersive] .brand{letter-spacing:.1em;font-size:31px}body[data-variant=astra-immersive] .header nav{gap:38px;font-size:18px}body[data-variant=astra-immersive] .hero{height:630px;padding-inline:5.1%}body[data-variant=astra-immersive] h1{letter-spacing:-.025em;font-weight:400;line-height:.93}body[data-variant=astra-immersive] .hero-subtitle{white-space:nowrap;margin-top:60px;font-size:26px;font-weight:500}body[data-variant=astra-immersive] .hero-intro{color:#f2f5f6;white-space:normal;margin-top:14px;font-size:24px}body[data-variant=astra-immersive] .hero-actions{gap:42px;margin-top:42px;font-size:23px}body[data-variant=astra-immersive] .primary{border-radius:0;min-height:67px;padding:13px 64px}body[data-variant=astra-immersive] .scene-switch button{background:0 0;border:0;border-bottom:3px solid #0000;min-width:auto;padding:8px 16px;font-size:18px}body[data-variant=astra-immersive] .scene-switch button[aria-pressed=true]{border-color:#89d9ef}body[data-variant=astra-immersive] .concept-caption{font-size:12px;bottom:37px}body[data-variant=sol-editorial]{--paper:#fff;--page-gutter:8%;--accent:#00569c}body[data-variant=sol-editorial] .opening{background:#fff}body[data-variant=sol-editorial] .hero{height:353px}body[data-variant=sol-editorial] h1{font-size:clamp(50px,4.95vw,76px);font-weight:700;line-height:.94}body[data-variant=sol-editorial] .hero-subtitle{margin-top:20px;font-size:25px}body[data-variant=sol-editorial] .hero-intro{margin-top:12px;font-size:15px}body[data-variant=sol-editorial] .hero-actions{margin-top:18px;font-size:15px}body[data-variant=sol-editorial] .primary{color:#00569c;background:0 0;border-color:#00569c;border-radius:10px;min-height:38px;padding:6px 24px}body[data-variant=sol-editorial] .hero-image{width:39%;height:314px;top:68px;left:53.2%}body[data-variant=sol-editorial] .concept-caption{background:#ffffffc9;padding:1px 4px;font-size:9px;bottom:26px;right:9%}body[data-variant=sol-editorial] .section{padding-block:48px}body[data-variant=sol-editorial] h2{font-size:32px;font-weight:600}@media (width>=1600px){.hero-copy{max-width:650px}.hero{height:600px}.hero-image{height:590px}.opening-dark .hero{height:600px}.opening-dark .hero-image{height:590px}}@media (width<=1200px){.hero-copy{max-width:48%}.hero-intro{white-space:normal}.hero-subtitle{font-size:23px}.header nav{gap:22px}.brand{font-size:22px}.hero-actions{gap:20px;font-size:15px}.scene-switch{gap:8px;left:55%}.scene-switch button{min-width:95px;padding:12px}.opening-dark .hero-copy{max-width:51%}body[data-variant=astra-immersive] .hero-subtitle{white-space:normal;font-size:23px}body[data-variant=astra-immersive] .hero-copy{max-width:68%}body[data-variant=astra-immersive] .hero-intro{font-size:21px}body[data-variant=astra-immersive] .hero-actions{font-size:18px}body[data-variant=astra-immersive] .header nav{gap:24px;font-size:15px}body[data-variant=sol-editorial] .hero-copy{max-width:50%}body[data-variant=sol-editorial] .hero-subtitle{font-size:20px}}@media (width<=760px){body{font-size:16px}.header{height:66px!important;margin:0!important;padding-inline:24px!important}.brand,body[data-variant=astra-immersive] .brand{font-size:21px}.header>nav{display:none}.menu-button{color:inherit;border-color:currentColor;padding:7px 12px;font-size:13px;display:block}.header .mobile-nav:not([hidden]){background:var(--paper);color:var(--ink);border:1px solid var(--line);z-index:10;flex-direction:column;gap:0;min-width:210px;padding:12px;display:flex;position:absolute;top:60px;right:20px;box-shadow:0 15px 35px #00182029}.mobile-nav a{padding:10px}.hero,.opening-dark .hero,body[data-variant=astra-immersive] .hero,body[data-variant=sol-editorial] .hero{height:auto;min-height:720px;padding:0 24px 270px}.hero-copy,.opening-dark .hero-copy,body[data-variant=astra-immersive] .hero-copy,body[data-variant=sol-editorial] .hero-copy{max-width:none;padding-top:38px}h1,body[data-variant=sol-editorial] h1{letter-spacing:-.035em;font-size:clamp(42px,10.8vw,66px)}body[data-variant=astra-immersive] h1{font-size:clamp(39px,10.2vw,64px);line-height:1.02}.hero-subtitle,body[data-variant=astra-immersive] .hero-subtitle,body[data-variant=sol-editorial] .hero-subtitle{white-space:normal;margin-top:24px;font-size:21px}.hero-intro,body[data-variant=astra-immersive] .hero-intro,body[data-variant=sol-editorial] .hero-intro{white-space:normal;margin-top:18px;font-size:16px}.hero-actions,body[data-variant=astra-immersive] .hero-actions,body[data-variant=sol-editorial] .hero-actions{flex-wrap:wrap;gap:20px;margin-top:26px;font-size:15px}.button,body[data-variant=astra-immersive] .primary{min-height:48px;padding:12px 20px}.hero-image,.opening-dark .hero-image,body[data-variant=astra-immersive] .hero-image,body[data-variant=sol-editorial] .hero-image{width:100%;height:290px;inset:auto 0 0}.opening-dark .hero-image:after,body[data-variant=astra-immersive] .hero-image:after{background:linear-gradient(var(--stage),transparent 28%)}body[data-variant=astra-immersive] .hero-image{height:340px}.hero-image img{object-position:center}.concept-caption,body[data-variant=sol-editorial] .concept-caption,.opening-dark .concept-caption,body[data-variant=astra-immersive] .concept-caption{font-size:9px;bottom:14px;right:24px}.scene-switch,body[data-variant=astra-immersive] .scene-switch{gap:8px;bottom:44px;left:24px}.scene-switch button,body[data-variant=astra-immersive] .scene-switch button{background:#031015ba;min-width:85px;padding:8px 12px;font-size:15px}.section{padding-block:52px}.section-head{margin-bottom:24px;display:block}.section-head>*+*{margin-top:16px}.desktop-break{display:none}body[data-variant=sol-editorial]{--page-gutter:24px}}@media (prefers-reduced-motion:reduce){:root{scroll-behavior:auto}*,:before,:after{transition:none!important;animation:none!important}}.levels{border-top:1px solid var(--line)}.level-columns{border-bottom:1px solid var(--line);grid-template-columns:repeat(3,1fr);gap:36px;min-height:256px;padding-block:26px;display:grid}.level-columns article{padding:8px 0;position:relative}.level-columns article+article{border-left:1px solid var(--line);padding-left:36px}.level-columns h3{font-size:21px;font-weight:500}.level-columns p{color:var(--muted);max-width:42ch;margin-top:18px;font-size:17px;line-height:1.5}.level-label{color:var(--accent);margin-top:14px;font-size:13px;display:block}.levels-astra{border:0;padding-top:46px}.levels-lead{border-bottom:1px solid var(--line);justify-content:space-between;align-items:end;gap:40px;padding:0 4px 30px;display:flex}.levels-lead p{margin-top:18px;font-size:25px;line-height:1.3}.levels-lead .text-link{white-space:nowrap;margin-bottom:8px;font-size:20px}.levels-pair{grid-template-columns:1fr 1fr;gap:50px;padding-block:28px 65px;display:grid}.levels-pair>div+div{border-left:1px solid var(--line);padding-left:50px}.levels-pair h3{font-size:34px;font-weight:600}.levels-pair p{max-width:53ch;color:var(--muted);margin-top:24px}.evidence{padding-top:42px}.topic-filters{flex-wrap:wrap;gap:6px;max-width:780px;font-size:14px;display:flex}.topic-filters button{border:0;border-radius:6px;min-height:42px;padding:8px 14px}.topic-filters button[aria-pressed=true]{color:#092332;background:#c0e1f0}.evidence .section-head{align-items:start}.evidence h2{flex-shrink:0}.evidence-heading,.evidence-row{grid-template-columns:23% 39% 38%;display:grid}.evidence-heading{letter-spacing:.05em;color:var(--muted);background:var(--wash);padding:12px 0;font-size:12px}.evidence-heading span{padding-inline:20px}.evidence-row{border-bottom:1px solid var(--line);padding-block:26px}.evidence-row>div{padding-inline:20px}.evidence-row h3{font-size:24px}.evidence-row p{font-size:16px;line-height:1.55}.evidence-row .topic-question{color:var(--muted);margin-top:12px;font-size:14px}.evidence-boundary{color:var(--muted)}.reference-links{color:var(--accent);flex-wrap:wrap;gap:8px 16px;margin-top:16px;font-size:13px;display:flex}.evidence-note{color:var(--muted);max-width:90ch;margin-top:24px;font-size:14px}.mobile-label{display:none}.evidence-art{object-fit:cover;width:100%;max-width:220px;height:135px;margin-bottom:18px}.evidence-optical .evidence-heading{display:none}.evidence-optical .evidence-row{grid-template-columns:22% 45% 33%}.evidence-optical .evidence-row:first-child{border-top:1px solid var(--line)}.evidence-optical .evidence-boundary{border-left:1px solid var(--line);padding-left:35px}.evidence-optical .section-head{display:block}.evidence-optical .topic-filters{max-width:none;margin-top:20px}.evidence-optical .topic-filters button{border:1px solid var(--line);border-radius:0}.evidence-editorial{padding-top:18px!important}.evidence-editorial .section-head{margin-bottom:14px}.evidence-editorial .topic-filters{max-width:620px;font-size:12px}.evidence-editorial .topic-filters button{border-radius:18px;min-height:32px;padding:4px 12px}.evidence-editorial .evidence-row{padding-block:18px}.evidence-editorial .evidence-row h3{font-size:18px;font-weight:600}.evidence-editorial .evidence-row p{font-size:14px}.evidence-editorial .topic-question{display:none}.editorial-thesis{border-top:1px solid var(--line);letter-spacing:-.02em;padding-block:14px 24px;font-size:29px;line-height:1.2}.evidence-editorial .evidence-row>div+div{border-left:1px solid var(--line)}@media (width<=1100px){.section-head{flex-wrap:wrap}.evidence .section-head{display:block}.topic-filters{max-width:none;margin-top:22px}.levels-lead{display:block}.levels-lead .text-link{margin-top:22px}.levels-lead p{font-size:22px}.level-columns{gap:22px}.level-columns article+article{padding-left:22px}}@media (width<=760px){.level-columns{padding-block:0;display:block}.level-columns article{padding:28px 0}.level-columns article+article{border-left:0;border-top:1px solid var(--line);padding:28px 0}.level-columns p{max-width:none}.level-label{margin-top:8px}.levels-astra{padding-top:38px}.levels-lead p{font-size:20px}.levels-lead .text-link{white-space:normal;font-size:15px}.levels-pair{grid-template-columns:1fr;gap:28px;padding-bottom:40px}.levels-pair>div+div{border-left:0;border-top:1px solid var(--line);padding:28px 0 0}.levels-pair h3{font-size:27px}.levels-pair p{margin-top:16px}.evidence-heading{display:none}.evidence-row,.evidence-optical .evidence-row{padding-block:28px;display:block}.evidence-row>div{border:0!important;padding:0!important}.evidence-row>div+div{margin-top:18px}.evidence-row h3{font-size:24px!important}.evidence-row p{font-size:16px!important}.mobile-label{color:var(--accent);margin-bottom:6px;font-size:12px;font-weight:600;display:block}.topic-filters{gap:4px}.topic-filters button{padding:8px 11px;font-size:13px}.evidence-art{display:none}.editorial-thesis{padding-block:28px;font-size:23px}}@media (width>=761px){body[data-variant=astra-immersive] .hero-actions{gap:51px;margin-top:26px}body[data-variant=astra-immersive] .scene-switch{gap:30px}.levels-pair{gap:0}.levels-pair>div:first-child{padding-right:50px}.levels-lead .text-link{font-size:19px}}body[data-variant=sol-light] h1{line-height:.95}body[data-variant=sol-light] .hero-subtitle{margin-top:34px}.header-theme{border-radius:20px;max-width:100px;padding:6px 10px;font-size:12px;line-height:1.25}.header nav{margin-left:auto;margin-right:32px}.section-side{max-width:32ch;color:var(--muted);font-size:16px}.clinician-grid,.pilot-layout,.contact-grid{grid-template-columns:1fr 1fr;gap:clamp(32px,6vw,100px);display:grid}.clinician-thesis{letter-spacing:-.025em;font-size:clamp(25px,2.6vw,40px);line-height:1.25}.clinician-thesis span{color:var(--muted)}.clinician-points p+p,.pilot-explanation p+p{margin-top:22px}.clinician-points strong{font-weight:600}.research-disclosure{border-block-end:1px solid var(--line);margin-top:24px}.research-disclosure summary{padding:22px 36px 22px 0;font-size:18px;list-style:none;position:relative}.research-disclosure summary:after{content:"";background:linear-gradient(var(--accent),var(--accent)) center/16px 1px no-repeat,linear-gradient(var(--accent),var(--accent)) center/1px 16px no-repeat;width:16px;height:16px;position:absolute;top:27px;right:8px}.research-disclosure[open] summary:after{background-size:16px 1px,0 0}.disclosure-body{max-width:92ch;padding:12px 0 32px}.disclosure-body p+p{margin-top:18px}.prose{overflow-wrap:anywhere;font-size:17px;line-height:1.75}.prose h1,.prose h2,.prose h3,.prose h4{letter-spacing:-.02em;margin:32px 0 18px;font-size:24px;line-height:1.3}.prose h1{font-size:30px}.prose p{margin-block:14px}.prose li{margin-block:9px}.prose table{border-collapse:collapse;width:100%;font-size:14px;display:block;overflow:auto}.prose td,.prose th{border:1px solid var(--line);text-align:left;min-width:150px;padding:12px}.prose blockquote{border-left:3px solid var(--accent);margin-left:0;padding-left:20px}.prose a{color:var(--accent)}.pilot-explanation h3{margin-bottom:22px}.pilot-measures{border-top:1px solid var(--line);margin-top:28px;padding-top:20px}.pilot-measures>span,.matrix-axis,.pilot-caption{color:var(--muted);font-size:13px}.pilot-measures p{margin-top:8px}.pilot-explanation>.text-link{margin-top:24px}.pilot-experiment{background:var(--wash);border:1px solid var(--line);padding:28px}.matrix-axis{justify-content:space-between;margin-bottom:18px;display:flex}.pilot-matrix{grid-template-columns:1fr 1fr;gap:12px;display:grid}.condition{text-align:left;background:var(--paper);border-radius:0;min-height:140px;padding:22px 18px;transition:background .2s,border-color .2s}.condition[aria-pressed=true]{border:2px solid var(--accent);background:#e8f6fa;padding:21px 17px}.condition-name{font-size:19px;line-height:1.25;display:block}.condition-flags{color:var(--muted);flex-direction:column;gap:6px;margin-top:20px;font-size:11px;line-height:1.4;display:flex}.condition-flags span:before{content:"";border:1px solid var(--accent);border-radius:50%;width:7px;height:7px;margin-right:7px;display:inline-block}.condition-flags span[data-enabled=true]:before{background:var(--accent)}.condition-detail{min-height:132px;margin-top:24px}.condition-detail h3{font-size:21px}.condition-detail p{margin-top:12px;font-size:15px}.pilot-caption{margin-top:20px}.pilot-controls{border-top:1px solid var(--line);grid-template-columns:1fr 2fr;gap:40px;margin-top:36px;padding-top:28px;display:grid}.pilot-controls p{color:var(--muted)}.grant-title{max-width:65ch;margin-bottom:38px;font-size:23px;line-height:1.4}.grant-work{counter-reset:work;grid-template-columns:repeat(4,1fr);gap:28px;display:grid}.grant-work article{border-top:1px solid var(--line);counter-increment:work;padding-top:20px}.grant-work article:before{content:"0"counter(work);color:var(--accent);margin-bottom:28px;font-size:13px;display:block}.grant-work h3{font-size:21px}.grant-work p{color:var(--muted);margin-top:16px;font-size:16px}.grant-roles{border-top:1px solid var(--line);margin-top:48px;padding-top:28px}.grant-roles dl{grid-template-columns:repeat(3,1fr);gap:32px;margin-top:24px;display:grid}.grant-roles dt{font-weight:500}.grant-roles dd{color:var(--muted);margin:10px 0 0}.grant>.text-link{margin-top:24px}.document-date{color:var(--muted);font-size:14px}.dossier-lead{justify-content:space-between;align-items:start;gap:40px;display:flex}.dossier-lead>p{max-width:65ch}.download-actions{flex-shrink:0;align-items:center;gap:22px;display:flex}.originals{margin-top:44px}.originals>p{max-width:85ch;color:var(--muted);margin-top:16px}.original-list{margin-block:28px}.original-list>a{border-top:1px solid var(--line);justify-content:space-between;gap:24px;padding:20px 0;text-decoration:none;display:flex}.original-list>a:last-child{border-bottom:1px solid var(--line)}.file-format{color:var(--accent);font-size:12px}.source-controls{grid-template-columns:2fr 1fr;gap:24px;margin-top:32px;display:grid}.source-controls label,form label{font-size:14px;font-weight:500;display:block}.source-controls input,.source-controls select,form input:not([type=checkbox]),form select,form textarea{background:var(--paper);border:1px solid var(--line);border-radius:0;width:100%;min-height:48px;margin-top:8px;padding:13px 14px;font-weight:400;display:block}.source-count{color:var(--muted);margin-block:22px;font-size:13px}.source{border-top:1px solid var(--line);scroll-margin-top:24px}.source:last-child{border-bottom:1px solid var(--line)}.source summary{grid-template-columns:50px 1fr 200px;gap:20px;padding:24px 30px 24px 0;list-style:none;display:grid;position:relative}.source summary:after{content:"";background:linear-gradient(var(--accent),var(--accent)) center/14px 1px no-repeat,linear-gradient(var(--accent),var(--accent)) center/1px 14px no-repeat;width:14px;height:14px;position:absolute;top:29px;right:0}.source[open] summary:after{background-size:14px 1px,0 0}.source-id{color:var(--accent);font-size:13px}.source-title strong{color:var(--muted);font-size:13px;font-weight:400}.source-title>span{margin-top:5px;font-size:17px;line-height:1.4;display:block}.source-direction{color:var(--accent);font-size:12px}.source-direction.excluded{color:#a33d35}.source-body{grid-template-columns:1.5fr 1fr;gap:48px;padding:0 0 28px 70px;display:grid}.source-body p+p{margin-top:12px}.source-findings p{font-size:16px}.source-limit{color:var(--muted)}.source-record{overflow-wrap:anywhere;color:var(--muted);font-size:13px}.source-record .text-link{color:var(--accent)}.contact-grid{grid-template-columns:1fr 1.1fr}.contact-alternative{color:var(--muted);margin-top:40px}form>label{margin-top:22px}.form-row{grid-template-columns:1fr 1fr;gap:18px;display:grid}.optional{color:var(--muted);font-size:12px;font-weight:400}.form-help{color:var(--muted);margin-top:8px;font-size:12px}.consent{align-items:start;gap:12px;font-size:12px;font-weight:400;line-height:1.55;display:flex}.consent input{width:18px;height:18px;accent-color:var(--accent);flex-shrink:0;margin:2px 0 0}form>.button{margin-top:24px}.form-status{min-height:24px;margin-top:16px;font-size:14px}.honeypot{width:1px;height:1px;position:absolute;left:-9999px;overflow:hidden}.footer{border-top:1px solid var(--line);color:var(--muted);grid-template-columns:1fr 1fr 1fr;gap:32px;padding-block:40px;font-size:13px;display:grid}.footer .brand{color:var(--ink)}.footer>div{justify-self:end}.footer p{margin-block:12px}.reading-theme{border-radius:20px;padding:8px 12px;font-size:12px}.download-page{max-width:900px;min-height:85vh;padding-block:80px}.download-page h1{margin-block:28px;font-size:clamp(36px,5vw,66px)}.download-page p{overflow-wrap:anywhere;margin-block:20px}.download-page .button{margin-block:16px}.download-page code{font-size:13px}.download-page .download-filename{color:var(--muted)}html[data-reading=dark]{--paper:#101d24;--ink:#e6eef1;--muted:#aabfc9;--line:#3a535f;--accent:#8ccee8;--wash:#1b333f;color-scheme:dark}html[data-reading=dark] body[data-variant=sol-light] .opening{color:#08151e;background:#f0f1ec}html[data-reading=dark] body[data-variant=sol-light] .opening .hero-intro,html[data-reading=dark] body[data-variant=sol-light] .opening .concept-caption{color:#4b5d68}html[data-reading=dark] .topic-filters button[aria-pressed=true],html[data-reading=dark] .condition[aria-pressed=true]{color:var(--ink);background:#294f61}html[data-reading=dark] .primary{color:#0b2430;background:#8ccee8;border-color:#8ccee8}html[data-reading=dark] .source-direction.excluded{color:#ffb4a8}@media (width<=1100px){.grant-work{grid-template-columns:1fr 1fr}.dossier-lead{display:block}.download-actions{margin-top:24px}.source summary{grid-template-columns:40px 1fr 150px;gap:12px}.source-body{gap:24px;padding-left:52px}.header nav{gap:20px;margin-right:20px}}@media (width<=760px){.header-theme{display:none}.header nav{margin:0}.clinician-grid,.pilot-layout,.contact-grid{grid-template-columns:1fr;gap:32px}.clinician-thesis{font-size:28px}.pilot-experiment{padding:18px}.pilot-matrix{gap:8px}.condition{min-height:155px;padding:18px 12px}.condition[aria-pressed=true]{padding:17px 11px}.condition-name{font-size:17px}.pilot-controls{grid-template-columns:1fr;gap:16px}.grant-work{gap:24px}.grant-work h3{font-size:19px}.grant-title{font-size:20px}.grant-roles dl{grid-template-columns:1fr;gap:20px}.source-controls{grid-template-columns:1fr;gap:18px}.source summary{grid-template-columns:32px 1fr;gap:10px;padding-right:22px}.source-direction{grid-column:2;margin-top:5px}.source-body{grid-template-columns:1fr;gap:24px;padding-left:0}.source-title>span{font-size:16px}.form-row{grid-template-columns:1fr;gap:22px}.footer{grid-template-columns:1fr;gap:16px}.footer>div{justify-self:start}.download-actions{flex-wrap:wrap}.original-list>a{gap:14px;font-size:15px}.research-disclosure summary,.prose{font-size:16px}.download-page{padding-block:40px}}body[data-variant=sol-light] .primary{background:#216b90;border-color:#216b90}html[data-reading=dark] body[data-variant=sol-light] .primary{color:#0b2430;background:#8ccee8;border-color:#8ccee8}body[data-variant=sol-light] .hero-subtitle{max-width:520px}body[data-variant=sol-light] .evidence h2{font-size:42px;font-weight:400}.evidence .section-head{border-bottom:1px solid var(--line);gap:24px;margin-bottom:16px;padding-bottom:14px}.evidence .topic-filters{flex:1;max-width:940px;font-size:13px}.evidence .topic-filters button{padding-inline:9px}.evidence-heading{border-top:1px solid var(--line)}.evidence-heading span+span{border-left:1px solid var(--line)}@media (width<=760px){body[data-variant=sol-light] .evidence h2{font-size:32px}.evidence .topic-filters{font-size:13px}.research-disclosure summary:after{top:25px}}body[data-variant=sol-editorial]{--paper:#fff;--ink:#08151e;--muted:#455d73;--line:#cfdee9;--wash:#eef4f8;--accent:#00569c;--page-gutter:8%;font-size:16px}body[data-variant=sol-editorial] .header{height:52px}body[data-variant=sol-editorial] .brand{letter-spacing:.15em;font-size:25px}body[data-variant=sol-editorial] .header nav{gap:28px;margin-right:28px;font-size:12px}body[data-variant=sol-editorial] .header-theme{padding:5px 9px;font-size:10px}body[data-variant=sol-editorial] .hero-subtitle{max-width:560px;margin-top:18px;line-height:1.25}body[data-variant=sol-editorial] .hero-image img{object-fit:contain}body[data-variant=sol-editorial] .hero-copy{max-width:560px;padding-top:15px}body[data-variant=sol-editorial] .hero-intro{white-space:normal;max-width:560px;margin-top:12px}body[data-variant=sol-editorial] .hero-actions{margin-top:18px}body[data-variant=sol-editorial] .primary{color:var(--accent);border-color:var(--accent);background:0 0}body[data-variant=sol-editorial] .editorial-thesis{padding:12px 0 24px;font-size:29px;line-height:1.22}body[data-variant=sol-editorial] .evidence .section-head{border:0;align-items:center;gap:18px;margin-bottom:12px;padding:0}body[data-variant=sol-editorial] .evidence .topic-filters{gap:3px;max-width:790px;font-size:11px}body[data-variant=sol-editorial] .topic-filters button{border-radius:18px;min-height:32px;padding:5px 10px}body[data-variant=sol-editorial] .evidence-heading{grid-template-columns:18% 42% 40%;padding:8px 0;font-size:10px}body[data-variant=sol-editorial] .evidence-row{grid-template-columns:18% 42% 40%;padding-block:12px}body[data-variant=sol-editorial] .evidence-row h3{font-size:16px}body[data-variant=sol-editorial] .reference-links{gap:6px 12px;margin-top:8px;font-size:11px}body[data-variant=sol-editorial] .evidence-note{margin-top:12px;font-size:12px}body[data-variant=sol-editorial] .pilot{padding-top:24px}body[data-variant=sol-editorial] .pilot .section-head h2{font-size:30px}body[data-variant=sol-editorial] .pilot .section-head h2 br{display:none}body[data-variant=sol-editorial] .pilot-layout{grid-template-columns:1fr 1.1fr;gap:48px}body[data-variant=sol-editorial] .pilot-experiment{background:var(--paper);padding:18px}body[data-variant=sol-editorial] .condition{background:var(--paper);border-radius:0;min-height:116px}body[data-variant=sol-editorial] .condition-name{font-size:17px}body[data-variant=sol-editorial] .grant-work{gap:24px}body[data-variant=sol-editorial] .section-head{margin-bottom:26px}body[data-variant=sol-editorial] .level-columns{min-height:210px}body[data-variant=sol-editorial] .level-columns h3{font-size:19px}body[data-variant=sol-editorial] .level-columns p{font-size:15px}html[data-reading=dark] body[data-variant=sol-editorial]{--paper:#101d24;--ink:#e6eef1;--muted:#aabfc9;--line:#3a535f;--accent:#8ccee8;--wash:#1b333f}html[data-reading=dark] body[data-variant=sol-editorial] .opening{color:#08151e;background:#fff}html[data-reading=dark] body[data-variant=sol-editorial] .opening .hero-subtitle,html[data-reading=dark] body[data-variant=sol-editorial] .opening .hero-intro,html[data-reading=dark] body[data-variant=sol-editorial] .opening .concept-caption{color:#455d73}html[data-reading=dark] body[data-variant=sol-editorial] .opening .primary{color:#00569c;background:0 0;border-color:#00569c}@media (width<=1200px) and (width>=761px){body[data-variant=sol-editorial] .hero-copy{max-width:49%}body[data-variant=sol-editorial] h1{font-size:clamp(48px,5vw,76px)}body[data-variant=sol-editorial] .hero-subtitle{font-size:21px}body[data-variant=sol-editorial] .hero-image{width:38%;top:65px;left:54%}body[data-variant=sol-editorial] .hero-intro{font-size:14px}body[data-variant=sol-editorial] .hero-actions{gap:20px}body[data-variant=sol-editorial] .header nav{gap:18px}}@media (width<=760px){body[data-variant=sol-editorial]{--page-gutter:24px}body[data-variant=sol-editorial] .hero{min-height:700px;padding-bottom:275px}body[data-variant=sol-editorial] .hero-copy{max-width:none;padding-top:38px}body[data-variant=sol-editorial] h1{font-size:46px}body[data-variant=sol-editorial] .hero-subtitle{margin-top:22px;font-size:21px}body[data-variant=sol-editorial] .hero-intro{margin-top:18px;font-size:15px}body[data-variant=sol-editorial] .hero-actions{gap:22px;margin-top:24px}body[data-variant=sol-editorial] .hero-image{width:100%;height:250px;padding-inline:24px;top:auto;bottom:0;left:0}body[data-variant=sol-editorial] .hero-image img{object-fit:cover}body[data-variant=sol-editorial] .concept-caption{bottom:8px;right:28px}body[data-variant=sol-editorial] .editorial-thesis{padding-block:24px;font-size:23px}body[data-variant=sol-editorial] .evidence-row{padding-block:24px;display:block}body[data-variant=sol-editorial] .evidence-row p{font-size:16px}body[data-variant=sol-editorial] .evidence-row h3{font-size:22px}body[data-variant=sol-editorial] .evidence .section-head{display:block}body[data-variant=sol-editorial] .evidence .topic-filters{margin-top:20px;font-size:12px}body[data-variant=sol-editorial] .topic-filters button{min-height:40px;padding:7px 11px}body[data-variant=sol-editorial] .pilot-layout{grid-template-columns:1fr;gap:28px}body[data-variant=sol-editorial] .pilot .section-head h2{font-size:30px}}body[data-variant=sol-editorial]{background:var(--paper)}body[data-variant=sol-editorial] .header-theme{max-width:130px;font-size:11px}body[data-variant=sol-editorial] .pilot .section-head h2 br:after{content:" "}body[data-variant=sol-editorial] .pilot .section-head h2{max-width:34ch}body[data-variant=sol-editorial] .header-search{color:#00569c;align-items:center;margin-right:16px;padding:8px;display:inline-flex}body[data-variant=sol-editorial] .evidence-note{max-width:none;font-size:11px;line-height:1.4}body[data-variant=sol-editorial] .evidence-row{padding-block:9px}body[data-variant=sol-editorial] .evidence-row p{font-size:12px;line-height:1.4}body[data-variant=sol-editorial] .evidence{padding-bottom:14px}.editorial-pilot-overview{margin-bottom:40px}.editorial-pilot-overview h2{font-size:28px;font-weight:600}.editorial-pilot-overview>p{color:var(--muted);margin-top:10px;font-size:13px}.overview-grid{border-top:1px solid var(--line);border-left:1px solid var(--line);grid-template-columns:1fr 1fr;margin-top:14px;display:grid}.overview-grid>button{text-align:left;border:0;border-right:1px solid var(--line);border-bottom:1px solid var(--line);align-items:center;gap:20px;padding:14px 20px;display:flex}.overview-grid>button[aria-pressed=true]{background:var(--wash);box-shadow:inset 0 -2px var(--accent)}.overview-icon{background:var(--wash);color:var(--accent);border-radius:50%;flex-shrink:0;justify-content:center;align-items:center;width:52px;height:52px;display:flex}.overview-grid strong{font-size:14px;font-weight:600;display:block}.overview-grid strong+span{color:var(--muted);margin-top:5px;font-size:12px;line-height:1.45;display:block}.overview-selection{min-height:20px}@media (width<=760px){.overview-grid{grid-template-columns:1fr}.overview-grid>button{gap:14px;padding:18px 12px}.overview-grid strong{font-size:16px}.overview-grid strong+span{font-size:14px}.editorial-pilot-overview h2{font-size:27px}body[data-variant=sol-editorial] .evidence-row p{font-size:16px}body[data-variant=sol-editorial] .header-search{margin-left:auto;margin-right:10px}.editorial-pilot-overview>p{font-size:15px}}body[data-variant=astra-immersive]{--paper:#f3f4f0;--ink:#08151e;--muted:#4b5d68;--accent:#12628b;--line:#b9cbd2;--wash:#d9edf5;--page-gutter:5.1%;background:var(--paper)}body[data-variant=astra-immersive] .header-theme{display:none}body[data-variant=astra-immersive] .header nav{gap:40px;margin:0 0 0 auto}body[data-variant=astra-immersive] .opening{color:#f5f8f9;background:#031015}body[data-variant=astra-immersive] .hero-image{width:66.41%;height:717px;top:0;right:0}body[data-variant=astra-immersive] .hero-image:after{background:linear-gradient(90deg,#031015 0%,#031015bb 8%,#0000 24%)}body[data-variant=astra-immersive] .hero-image img{object-fit:cover;object-position:center;width:100%;height:100%;transition:filter .65s cubic-bezier(.16,1,.3,1)}body[data-variant=astra-immersive] .hero-actions{gap:42px;margin-top:42px}body[data-variant=astra-immersive] .hero-copy{max-width:720px;padding-top:98px}body[data-variant=astra-immersive] .hero-intro{max-width:570px;margin-top:14px}body[data-variant=astra-immersive] .primary{color:#031015;background:#85d4ec;border-color:#85d4ec;min-height:67px;padding:13px 64px;font-weight:500}body[data-variant=astra-immersive] .scene-switch{gap:30px;bottom:26px;left:48%}body[data-variant=astra-immersive] .scene-switch button{min-width:76px;min-height:44px;line-height:1.2}body[data-variant=astra-immersive] .concept-caption{color:#c3d0d6;font-size:12px;bottom:37px}body[data-variant=astra-immersive] .opening[data-scene=sound] .hero-image img{filter:saturate(.3)brightness(.72)}body[data-variant=astra-immersive] .opening[data-scene=light] .hero-image img{filter:saturate(.78)brightness(1.08)}body[data-variant=astra-immersive] .opening[data-scene=combined] .hero-image img{filter:none}body[data-variant=astra-immersive] .levels-lead h2{font-size:48px;font-weight:500}body[data-variant=astra-immersive] .levels-lead p{font-size:25px}body[data-variant=astra-immersive] .levels-pair h3{font-size:34px}body[data-variant=astra-immersive] .levels-pair{padding-bottom:58px}body[data-variant=astra-immersive] .evidence{padding-top:56px}body[data-variant=astra-immersive] .section-head{gap:32px}body[data-variant=astra-immersive] .section-head h2{max-width:25ch}html[data-reading=dark] body[data-variant=astra-immersive]{--paper:#101d24;--ink:#e6eef1;--muted:#aabfc9;--line:#3a535f;--accent:#8ccee8;--wash:#1b333f}html[data-reading=dark] body[data-variant=astra-immersive] .opening{color:#f5f8f9;background:#031015}@media (width>=761px) and (width<=1200px){body[data-variant=astra-immersive] .header nav{gap:24px;font-size:15px}body[data-variant=astra-immersive] .brand{font-size:26px}body[data-variant=astra-immersive] .hero-copy{max-width:68%;padding-top:100px}body[data-variant=astra-immersive] .hero-subtitle{white-space:normal;max-width:560px;font-size:23px}body[data-variant=astra-immersive] .hero-intro{max-width:490px;font-size:21px}body[data-variant=astra-immersive] .hero-actions{gap:28px;font-size:18px}body[data-variant=astra-immersive] .primary{padding:13px 40px}body[data-variant=astra-immersive] .scene-switch{gap:16px;left:50%}body[data-variant=astra-immersive] .levels-lead h2{font-size:40px}}@media (width<=760px){body[data-variant=astra-immersive]{--page-gutter:24px}body[data-variant=astra-immersive] .hero{min-height:840px;padding:0 24px 360px}body[data-variant=astra-immersive] .hero-copy{max-width:none;padding-top:44px}body[data-variant=astra-immersive] h1{font-size:clamp(38px,9.9vw,60px);line-height:1.03}body[data-variant=astra-immersive] .hero-subtitle{white-space:normal;margin-top:28px;font-size:21px;line-height:1.35}body[data-variant=astra-immersive] .hero-intro{margin-top:20px;font-size:17px;line-height:1.5}body[data-variant=astra-immersive] .hero-actions{align-items:center;gap:20px;margin-top:26px;font-size:15px}body[data-variant=astra-immersive] .primary{min-height:50px;padding:12px 20px}body[data-variant=astra-immersive] .hero-image{width:100%;height:380px;inset:auto 0 0}body[data-variant=astra-immersive] .hero-image:after{background:linear-gradient(#031015,#0000 35%)}body[data-variant=astra-immersive] .hero-image img{object-position:center 42%}body[data-variant=astra-immersive] .scene-switch{justify-content:center;gap:14px;bottom:52px;left:24px;right:24px}body[data-variant=astra-immersive] .scene-switch button{background:#031015cf;padding:10px 14px;font-size:16px}body[data-variant=astra-immersive] .concept-caption{font-size:10px;bottom:16px;right:24px}body[data-variant=astra-immersive] .levels-lead h2{font-size:34px}body[data-variant=astra-immersive] .levels-lead p{font-size:20px}body[data-variant=astra-immersive] .levels-pair h3{font-size:27px}body[data-variant=astra-immersive] .levels-pair{padding-bottom:40px}body[data-variant=astra-immersive] .header .mobile-nav{background:var(--paper);color:var(--ink);margin:0}body[data-variant=astra-immersive] .section-head{display:block}}@media (prefers-reduced-motion:reduce){body[data-variant=astra-immersive] .hero-image img{transition:none}}@media (width>=761px){body[data-variant=astra-immersive] .hero-intro{margin-top:8px}body[data-variant=astra-immersive] .hero-actions{gap:44px;margin-top:32px}body[data-variant=astra-immersive] .primary{padding-inline:66px}}@media (width<=760px){body[data-variant=astra-immersive] .hero{min-height:760px}}@media (width>=761px){body[data-variant=astra-immersive] .brand{letter-spacing:.145em;font-weight:400}body[data-variant=astra-immersive] .hero-actions>.text-link{border-bottom:2px solid #88d8ee;padding-bottom:5px;font-size:21px;line-height:1.3}}body[data-variant=astra-immersive] .opening .primary{color:#031015;background:#86cfec;border-color:#86cfec}body[data-variant=astra-immersive] .scene-switch button{border-bottom-color:#0000;position:relative}body[data-variant=astra-immersive] .scene-switch button[aria-pressed=true]{border-bottom-color:#0000}body[data-variant=astra-immersive] .scene-switch button[aria-pressed=true]:after{content:"";background:#89d9ef;width:106px;height:3px;position:absolute;bottom:-2px;left:50%;transform:translate(-50%)}@media (width<=760px){body[data-variant=astra-immersive] .scene-switch button[aria-pressed=true]:after{width:100%}}.variant-links .section-intro{margin-top:0;margin-bottom:28px}.variant-links-grid{grid-template-columns:repeat(3,minmax(0,1fr));gap:24px;display:grid}.variant-link{border-block:1px solid var(--line);flex-direction:column;justify-content:space-between;gap:24px;min-height:140px;padding:24px 0;text-decoration:none;display:flex}.variant-link-name{font-size:22px;font-weight:500;line-height:1.25}.variant-link-meta{color:var(--muted);font-size:13px}.variant-link[aria-current=page]{border-top:3px solid var(--accent);padding-top:22px}.comparison-header{border-bottom:1px solid var(--line);justify-content:space-between;align-items:center;gap:24px;padding-block:28px;display:flex}.comparison-header>span{color:var(--muted);font-size:14px}.comparison-intro{max-width:1100px;padding-block:72px 48px}.comparison-intro h1{max-width:17ch;font-size:clamp(42px,5.5vw,78px);line-height:1.05}.comparison-intro>p{max-width:64ch;color:var(--muted);margin-top:24px;font-size:21px}.comparison-grid{grid-template-columns:repeat(3,minmax(0,1fr));gap:32px;padding-bottom:64px;display:grid}.comparison-item{border-top:1px solid var(--line);padding-top:20px}.comparison-image{background:var(--wash);aspect-ratio:4/3;margin-bottom:24px;display:block;overflow:hidden}.comparison-image img{object-fit:cover;width:100%;height:100%;transition:transform .4s ease-out;display:block}.comparison-image:hover img{transform:scale(1.025)}.comparison-item h2{min-height:2.3em;font-size:28px}.comparison-item p{color:var(--muted);margin-top:16px}.comparison-item .button{margin-top:24px}.comparison-item .comparison-author{margin-top:10px;font-size:13px}.comparison-note{border-top:1px solid var(--line);max-width:900px;color:var(--muted);padding-block:32px 64px}@media (width>=761px) and (width<=1100px){.header>nav:not(.mobile-nav),.header-theme{display:none}.header .menu-button{color:inherit;border-color:currentColor;padding:8px 14px;display:block}.header .mobile-nav:not([hidden]){background:var(--paper);color:var(--ink);border:1px solid var(--line);z-index:10;flex-direction:column;gap:0;min-width:220px;margin:0;padding:12px;display:flex;position:absolute;top:62px;right:24px}.header .mobile-nav a{padding:10px}}@media (width<=760px){.variant-links-grid,.comparison-grid{grid-template-columns:1fr;gap:24px}.variant-link{gap:16px;min-height:112px}.comparison-header{padding-block:24px}.comparison-header>span{text-align:right;max-width:12ch;font-size:12px}.comparison-intro{padding-block:44px 32px}.comparison-intro>p{font-size:18px}.comparison-item h2{min-height:0}.comparison-grid,.comparison-note{padding-bottom:40px}}@media (prefers-reduced-motion:reduce){.comparison-image img{transition:none}}